cause of offense; cause of offence; annoyance; spasms; convulsions; cramps
passion; temper; irritability
to irritate; to grate on one's nerves; to aggravate; to be galling; to be invidious
to lose one's temper; to throw a tantrum
fit of anger; temper; rage; firecracker
irritant; cause of irritation; cause of annoyance