ききめ
Meanings
Noun
1. effect; virtue; efficacy; impression
2. one's dominant eye
Pitch accent
きめ
Composed of
effectiveness; efficacy; dominance (e.g. of left or right hand); tasting (alcohol, tea, etc.)
eye; eyeball; eyesight; sight; look; stare; notice
Examples (2 in total)
The effects of the medicine were wearing off.
Your advice will have no effect on them.